This is an almost completely true account of me using ARB today.
Apart from discovering the button that kills people in ARB, today was the first day that I thought about the absurdity of using 3 different alignment programs to get my work done:
- I use SeaView to align my sequences and to view already-aligned sequences.
- I use Clustal primarily for its “range information” function, to trim my sequences at my conserved trim targets.
- I use ARB to import the alignments and make phylogenetic trees.
Perhaps one day, there will be one aligner program that does everything I need it to. Do you hear me, you bioinformaticists out there??