Aryon’s Corpus Disease Paper

I’d been reading a whole lot of immunology papers lately, and I became obsessed with the idea of Master Aryon writing a paper on his studies of Corpus disease. I figure since he did his early work in the Corpusarium (and has a Restoration skill of 90), he probably wrote up his findings a few times. Also the game has other academic writings like “Itermerel’s Notes” and “Kagouti Mating Habits,” so there’s precedent for that sort of thing.

Master Aryon writing a paper on his Corpus disease study

I honestly spent way too much time trying to decide if Aryon would use t-SNE or UMAP for the dimensionality reduction of his cell expression data, even though neither algorithm even existed yet when Morrowind came out.

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Yoyo Swab Results

I have photographed the results of swabbing yoyos onto LBA plates. Of course this wasn’t an experimentally rigorous test and we can’t tell anything quantitative from it, but still it does appear that the “hand” swabs had visibly different community than the yoyos. Given that the hands had a ton of yellow colonies, I’m going to just assume that those were mostly Micrococcus luteus, since M. luteus is commensal on skin and whenever I’ve sequenced colonies that looked like that in the past they were M. luteus (and most likely contaminants from skin).

Other notable observations were:

The hand replicates were Doc’s left and right hand. One of them seems so have had way more bacteria than another… although again our methods weren’t quantitative (I could have just so happened to have swabbed the one chunk on his hand that had all the bacteria, etc).

The negative controls did not have any growth whatsoever – so I guess my sterile technique is still pretty good.

And now, the results!

Hands (“positive control”):

LBA Plates
LBA Plates

Wooden yoyo:

LBA Plates
LBA Plates

Metal (aluminum) yoyo:

LBA Plates
LBA Plates

Plastic (delrin) yoyo:

LBA Plates
LBA Plates

Negative Controls (the same water and swabs we were using for the rest of the swabs, but without having swabbed anything):

LBA Plates
LBA Plates
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Yoyo Swabs

This weekend, we plated some swabs of yoyos onto LB, for fun. We’ll see what grows!

Swabbing yoyos
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